Jan. 10, 2026 at 11:45 AM ET5 min read

Heron Therapeutics’ Revenue Soars Beyond Expectations in Q4 2025

Tim BohenAvatar
Written by Tim Bohen
Reviewed by Ben Sturgill Fact-checked by Ellis Hobbs

Heron Therapeutics Inc.’s stock surged 12.6% amid positive sentiment driven by promising FDA designations and results.

Key Highlights:

  • Heron Therapeutics announces its Q4 revenue reached $40.5M, exceeding consensus estimates of $39.83M, driven largely by contributions from the Acute Care franchise.
  • ZYNRELEF, a key product for post-surgical pain management, played a significant role with contributions of $12.5M, underscoring its critical impact in the portfolio.
  • The company’s full-year net revenue for 2025 surged to approximately $154.9M, representing a notable quarterly growth for ZYNRELEF, which saw the largest revenue increase quarter-over-quarter.
  • With robust performances from both ZYNRELEF and APONVIE, Heron Therapeutics demonstrated strong market positioning amid growing demand for their innovative treatments in acute care.
  • These financial outcomes may bolster investor confidence, potentially leading to a positive market reaction for HRTX shares.

Healthcare industry expert:

Analyst sentiment – positive

Heron Therapeutics (HRTX) exhibits a challenging market position amidst disappointing profitability ratios, as evidenced by an EBIT margin of -8.3% and a gross margin of 73.9%. Despite a 5-year revenue growth rate of 8.51%, the company struggles with a pre-tax profit margin of -100%. Significant liabilities, reflected in a leverage ratio of 35.5, and weak return on assets at -45.82%, constrain financial strength. However, a current ratio of 2.6 denotes adequate short-term liquidity. Negative equity and a price-to-tangible book value of -8.54 underline urgent needs for balance sheet improvements to sustain operations.

Technical analysis reveals a gradual uptick in HRTX’s weekly price patterns from $1.24 to $1.43, indicating a nascent bullish trend. The recent high of $1.44 suggests potential resistance, warranting close monitoring for a breakout above this level. Notable upward momentum was observed from the open of $1.28 to a close of $1.43. Trading volumes should remain a focus, as sustained interest can affirm the continuation of this trend. A prudent trading strategy would be to capitalize on dips near the $1.28 support level, positioning for gains amid rising buy signals that could propel a move beyond the $1.44 resistance.

Recent catalysts strengthen the outlook for Heron Therapeutics. The company reported Q4 revenue of $40.5 million, exceeding estimates, driven by the success of ZYNRELEF and APONVIE within its Acute Care franchise. Achieving full-year revenue of $154.9 million, Heron marked notable growth compared to its Healthcare and Biotechnology & Life Sciences peers. The largest quarter-over-quarter increase attributable to ZYNRELEF highlights the potential for further advances. As such, HRTX shows promise with price targets anticipated to reach $1.60, assuming the current trajectory continues without adverse market shocks.

Candlestick Chart

Weekly Update Jan 05 – Jan 09, 2026: On Saturday, January 10, 2026 Heron Therapeutics Inc. stock [NASDAQ: HRTX] is trending up by 12.6%! Discover the key drivers behind this movement as well as our expert analysis in the detailed breakdown below.

Quick Financial Overview

Heron Therapeutics’ unaudited financial results for the fourth quarter reveal a commendable achievement with $40.5M in net revenue, surpassing analyst expectations. The star performer remained ZYNRELEF, contributing $12.5M during this period. Such strong performance showcases the product’s growing adoption within the healthcare community as a preferred option for managing postoperative pain. Moreover, the full-year figures highlight a substantial increase in sales, with overall net revenue climbing to approximately $154.9M in 2025. This rapid expansion underscores not only the market’s trust in Heron’s offerings but also strategic execution in advancing their Acute Care franchise’s reach.

Financially, Heron continues to grapple with certain challenges. Despite positive revenue trends, key profitability ratios reveal ongoing struggles—evident from negative ebit margins, profit margins, and return on assets. The firm’s financial strength, however, remains buoyed by a favorable current ratio of 2.6, which projects healthy liquidity. Additionally, Heron’s high gross margin of 73.9% reflects efficient cost management despite broader operational inefficiencies. Valuation measures indicate a cautious outlook, particularly with consideration to price-to-sales and book value ratios, offering mixed signals to potential investors. Nevertheless, these financial pivots could offer pivotal insights into the stock’s performance trajectory, amplified by recent earnings announcements.

This is stock news, not investment advice. StocksToTrade News delivers real-time stock market updates tailored to highlight the key catalysts driving short-term price movements. Our coverage is designed for active traders and investors who thrive in fast-moving markets, with a focus on volatile sectors like penny stocks, AI stocks, Robinhood stocks and other momentum plays. From earnings reports and FDA approvals to mergers, new contracts, and unusual trading volume, we break down the events that can spark significant price action.

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