Nov. 20, 2025 at 5:15 PM ET7 min read

Guardant Health Stock Soars with Blood Test Expansion and Strong Q3 Results

Tim BohenAvatar
Written by Tim Bohen
Reviewed by Ben Sturgill Fact-checked by Ellis Hobbs

Guardant Health Inc.’s stock has been trading up by 5.84 percent following promising clinical trial results boosting investor confidence.

Key Takeaways

  • A revolutionary leap in cancer treatment monitoring was announced with Guardant Health’s expansion of the Guardant Reveal blood test to late-stage solid tumor patients.
  • Financial projections climb dramatically as Q3 earnings exceed expectations, raising the full-year forecast and boosting investor confidence.
  • Strategic alliance with Zephyr AI aims to further precision oncology through innovative biomarker identification.
  • Citi, Canaccord, and others significantly increase their price targets on GH, highlighting expected growth and management’s recent strong performance.
  • Positive momentum continues with the latest revenue projections and extension of their product line, all hinting at a strong future for GH.

Candlestick Chart

Live Update At 12:14:12 EST: On Thursday, November 20, 2025 Guardant Health Inc. stock [NASDAQ: GH] is trending up by 5.84%! Discover the key drivers behind this movement as well as our expert analysis in the detailed breakdown below.

Quick Financial Overview

Guardant Health Inc.’s recent earnings report displays an impressive and uplifting picture, to say the least. For the third quarter of 2025, revenue hit $265.2 million, well above the consensus estimate of $235.7 million. This revenue beat was also coupled with an EPS of -39c, outperforming the -49c projected by analysts. These surprising numbers presented a picture of a company clearly on the move, bolstering faith among both investors and industry observers.

The stock market quickly absorbed the news, sending Guardant Health shares up by 16% to a new price of $84.00, following this earnings reveal. But it wasn’t just the Q3 figures that energized the bulls; the company also revised its 2025 revenue guidance upwards, presenting a much stronger outlook for the year ahead. From $915 million to $965-$970 million, this substantial uplift, driven by growing oncology revenue, reflects over 31% year-over-year growth – a testament to the successful integration and scaling of their technology adjunct.

Regarding key financial figures, despite a challenging landscape, GH has managed an 18% net income continuous operation increase, celebrating an EBIT margin of -32.3% reflecting an ongoing investment strategy. Income statements indicate a total revenue of $739 million, where gross margins maintained at a stunning 72.4%, reinforcing Guardant Health’s competitive market positioning.

Among other highlights, strategic investments are clearly visible in the ongoing cash flow maneuvers where operating cash flow stands at -$35.41 million, with a capital expenditure totaling close to $10.35 million. This reiterates a focused approach towards organic growth through widened R&D initiatives and execution of key expansion strategies.

Market Reactions: Insight into Recent Developments

The buzz surrounding Guardant Health’s new expansions in their blood test capabilities cannot be understated. Outdoing traditional methods, their improved Guardant Reveal blood test now includes monitoring mechanisms for late-stage solid tumor therapies. This innovation not only fast-tracks treatment, allowing for real-time adjustments but also positions GH as a pivotal player in precision oncology. The idea of early disease progression detection is spun into real-world application, drawing significant attention from medical circles worldwide and opening discussions around enhanced patient outcome potentials.

Adding more to the charm, a recently forged partnership with Zephyr AI marks a substantial move on the strategic chessboard. This collaboration aims to enhance drug response predictions. The integration of AI into multimodal molecular data is anticipated to yield groundbreaking insights aimed at pushing personalized oncology treatments to new horizons. When companies dare to merge AI and healthcare, the stakes are always high, but the possible rewards too enormous to ignore. This daring move promises to uplift Guardant Health’s market position and revenues, as digital augmented insights reshape the future of oncological treatments.

Guardant Health’s momentum is also reflected in the overwhelming analyst response post earnings report. Analysts from Citi, Canaccord, and beyond have raised their price targets, now eyeing $100 per share as a fair valuation baseline. The upward revision follows comprehensive views of robust sales beat across the board and reflects anticipated expansive growth.

Finally, while GH has been painting a holistic growth picture, it’s also interesting to note the significant participation in other fiscal avenues, like strategic equity offerings and senior notes. Earlier this month, they priced their public offering at $90 per share, netting proceeds for general corporate purposes and potential repurchase of notes.

Taking all these factors into account, the current and potential investor sentiment is rocking sky-high. As the company steps forward with strategic expansions, partnerships, and product growth, they also brace themselves to reconstruct how cancer is approached at its core. Let’s not overlook that the stock market rarely misses to award such tenacity, and with innovation this vivid, Guardant Health’s journey is one for the books.

Conclusion

Summing up the cascade of events, Guardant Health’s present market journey shines as a beacon for an evolving healthcare future. From revenue uprising and earnings satisfaction to mindfully crafted partnerships and daring expansions, GH is hitting its stride with deft and determination. Expectedly, this whirlwind of developments keeps this robust enterprise in the bull’s radar, promising a steadfast trajectory for traders seeking long-term value.

As Tim Bohen, lead trainer with StocksToTrade says, “I focus on momentum that’s visible right now. Speculation on future moves is outside my playbook.” A fluid interplay of innovation, market strategic pivots, and financial strength underlines not just a company poised for success but also a testament to endurance and harmonious growth. Substantial roads stretch ahead for Guardant Health; all eyes & ears remain keen on how this narrative unfolds.

As traders, analysts, and stakeholders, it’s a thrilling time to be watching, and perhaps confronting the fact that, much like life, the financial market knows how to celebrate promise and progression. So for now, Guardant Health rides the wave, and what a wave it is!

This is stock news, not investment advice. StocksToTrade News delivers real-time stock market updates tailored to highlight the key catalysts driving short-term price movements. Our coverage is designed for active traders and investors who thrive in fast-moving markets, with a focus on volatile sectors like penny stocks, AI stocks, Robinhood stocks and other momentum plays. From earnings reports and FDA approvals to mergers, new contracts, and unusual trading volume, we break down the events that can spark significant price action.

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