Nov. 8, 2025 at 11:50 AM ET6 min read

Soleno Therapeutics Shares Surge Following Robust Q3 Earnings

Tim BohenAvatar
Written by Tim Bohen
Reviewed by Ben Sturgill Fact-checked by Ellis Hobbs

Soleno Therapeutics Inc.’s stocks have been trading up by 10.24 percent following promising clinical trial results.

Key Highlights

  • Earnings for Q3 recorded an impressive 47 cents per share, significantly surpassing analyst expectations of just 6 cents.
  • Revenue soared to $66M, outperforming projections of $48.09M, driven by strong sales of VYKAT XR.
  • Despite reporting profits and exceeding revenue forecasts, shares experienced a notable after-hours decline of more than 22%.
  • VYKAT XR, a therapy for hyperphagia in Prader-Willi Syndrome patients, has been credited with the company’s return to profitability.
  • Strategic moves, such as appointing financial expert Mark Hahn to the board, suggest a robust foundation for future growth.

Healthcare industry expert:

Analyst sentiment – positive

Soleno Therapeutics (SLNO) is currently exhibiting mixed fundamentals. While the company has achieved impressive milestone profitability with a Q3 net income of $26M, various financial metrics reveal underlying challenges. Specifically, a negative EBIT margin of -76.8% and a return on assets of -28.49% indicate ongoing operational inefficiencies. However, an astounding gross profit margin of 98.1% suggests potential in product sales and cost management. The financial stability is further reinforced with a current ratio of 16.1, showcasing considerable liquidity, despite a high enterprise value to sales ratio of 71.61, suggesting market overvaluation risks.

Technically, Soleno’s recent trading activity demonstrates significant volatility, with weekly prices showing a downward trajectory. The consistent decline from $65.65 to $43.54 before a slight recovery to $48 suggests a potential bearish trend. Short-term candle patterns indicate a possible oversold condition, suggesting a rebound opportunity for active traders. However, with declining volumes as the prices dipped, caution is advised. A pragmatic trading strategy would involve setting stop-loss orders near $42.86 and targeting a retracement to $51.13, provided volumes confirm a reversal.

Catalysts for Soleno Therapeutics include its strong Q3 performance, driven by the successful commercialization of VYKAT XR, an FDA-approved drug for Prader-Willi Syndrome. Despite a Wells Fargo price target downgrade to $106, the company has noteworthy growth prospects as Vykat XR is projected as a billion-dollar drug. However, recent M&A rumors, combined with a surprising post-earnings sell-off, underscore market volatility. Comparatively, Soleno is outperforming sector benchmarks, yet its share price instability poses challenges. Support is pegged around $42, and resistance at $51, while the outlook remains cautiously optimistic given the sales trajectory and pending market reception.

Candlestick Chart

More Breaking News

Weekly Update Nov 03 – Nov 07, 2025: On Saturday, November 08, 2025 Soleno Therapeutics Inc. stock [NASDAQ: SLNO] is trending up by 10.24%! Discover the key drivers behind this movement as well as our expert analysis in the detailed breakdown below.

Quick Financial Overview

In an impressive turnaround, Soleno Therapeutics posted a robust financial performance in the third quarter of 2025, highlighted by a remarkable revenue increase. The company reported a revenue of $66M, significantly above the $48.1M projected by market analysts. This revenue surge can be mainly credited to the enthusiastic market reception of VYKAT XR, an FDA-approved treatment for hyperphagia in Prader-Willi Syndrome patients. Such performance not only highlights the company’s strategic positioning but also its potential as a market leader in the specialized biotechnology field.

This growth is further underlined by the fact that Soleno achieved a net income of $26M, marking its transition from a previous year’s loss to profitability. The earnings per share dramatically surpassed expectations, providing a clear indication of the company’s improving operational efficiencies and market savvy. However, despite these impressive metrics, shares experienced a steep fall of over 22% after hours. This volatility could be attributed to profit-taking or concerns over future sustainability against teetering growth expectations sparked by recent market corrections.

Key financial ratios paint a mixed picture. A high gross margin of 98.1% reflects strong product pricing power, yet other ratios like return on assets at -28.49 indicate there is much room for improvement in efficiency. The wide-ranging negative profitability margins suggest past challenges, though recent achievements are promising. The current ratio at 16.1 portrays robust liquidity, affirming solid short-term financial health.

Conclusion

Soleno Therapeutics finds itself at a pivotal crossroads, defined by recent financial successes and strategic outlook assessments. Its ability to translate impressive quarterly results into sustained market momentum hinges largely on strategic diversification and effective navigation of evolving sectoral dynamics. While traders share a healthy skepticism reflected in post-earnings volatilities, the company’s robust financial health and improving profitability metrics give it a fortified stance to leverage future opportunities. As Tim Bohen, lead trainer with StocksToTrade says, “I never chase price. The best opportunities allow me to enter on my terms, not when I’m feeling pressured.” This philosophy resonates with Soleno’s approach as it focuses on strategic initiatives, potential new market expansions, and calculated M&A maneuvers that could cement its standing as a competitive player in the healthcare and biotechnology sectors. As it continues to refine its roadmap, these elements will be critical for sustaining trader confidence and long-term shareholder value.

This is stock news, not investment advice. StocksToTrade News delivers real-time stock market updates tailored to highlight the key catalysts driving short-term price movements. Our coverage is designed for active traders and investors who thrive in fast-moving markets, with a focus on volatile sectors like penny stocks, AI stocks, Robinhood stocks and other momentum plays. From earnings reports and FDA approvals to mergers, new contracts, and unusual trading volume, we break down the events that can spark significant price action.

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